Junction-specific peptide detection and alternative splicing

We are developing a computational method to analyze proteomics data for the detection of junction-specific peptide and alternative splicing. In details, we will

  • Identify the human junction-specific peptides using information from the exon database we created;
  • Assign confidence for junction-specific peptides using the fragment ions in MS/MS spectra;
  • Modeling alternative splicing using junction-specific peptide information

<Weihong Xu and Soyoung Ryu>

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